The design and synthesis of genomes provides a powerful approach for understanding and engineering biology 1,2,3,4,5,6. Genome synthesis has the potential to elucidate synonymous codon function 7, ...
Living organisms synthesize a staggering variety of proteins by combining 20 amino acids into chains of any length and order. In the past, to expand protein diversity beyond the scope of these 20 ...
61 codons specify one of the 20 amino acids that make up proteins 3 codons are stop codons, which signal the termination of protein synthesis Importantly, the genetic code is nearly universal, shared ...
Scientists explored mRNA and protein public databases to unravel hidden meanings of the genetic code. Using a metric derived from mRNA codon composition, they found out how gene sequence choice can ...
Researchers at the Medical Research Council Laboratory of Molecular Biology have successfully rewritten the DNA makeup of the bacteria Escherichia coli, or E. coli. As stated in the paper detailing ...
Today, thousands of databases with biological data are publicly available. They include data on gene and protein sequences and detailed measurements of different cellular parameters, such as the exact ...