Gene sequences for targets that have been identified by genomics approaches are cloned and expressed as target proteins that are suitable for screening with a probe library of small, drug-like ...

Combinatorial designs and finite group theory form a rich intersection of discrete mathematics and algebra, where structured arrangements of elements are studied alongside the algebraic properties of ...

ABSTRACT Performing system-level trade studies during the design of complex systems has many benefits in terms of performance, reliability, and cost. However, current engineering practices often do ...

Objective: The development of a generalizable, fast, effective, scalable, translatable and economic purification platform is critical for the technical and economic success of mRNA-based therapeutics.

This paper reports laboratory experiments that evaluate the performance of a flexible package bidding format developed by the FCC, in comparison with other combinatorial formats. In general, the ...