It has long been thought that two enzymes, the kinases CDC7 and CDK2, are both needed to trigger DNA replication in mammalian cells. This view is challenged by evidence that offers a revised view of ...

Life on Earth depends on the ability of cells to duplicate their genetic material, encoded in DNA molecules, and pass this information on to the next generation. Elucidation of the molecular mechanism ...

Enzymes, which are crucial to controlling how cells replicate in the human body, could be the very ingredient that encourages DNA to spontaneously mutate -- causing potentially permanent genetic ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

DNA replication is one of the most important processes in biology, responsible for ensuring that a cell's genetic material is copied over to new cells efficiently during cell division. But what ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications, an ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...