Missense variants remain a challenge in genetic interpretation due to their subtle and context-dependent effects. While current prediction models perform well in known disease genes, generalizability ...
Researchers have developed EVE-Vax, an AI tool that forecasts viral mutations and designs test proteins to guide next-generation vaccines. The breakthrough could allow scientists to build vaccines ...
Whether we are predisposed to particular diseases may depend to a large extent on variations in our genomes, but the influence on the presentation of certain pathological traits of genetic variants ...
CoVFit can predict the epidemic potential—i.e., the fitness—of SARS-CoV-2 variants based solely on their spike protein sequences. Viral infectious diseases pose significant challenges due to the rapid ...
Two of the traits that set modern humans apart from non-human primates are taller stature and a higher basal metabolic rate. Publishing in the Cell Press journal Cell Genomics on May 21, researchers ...
This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...
Morning Overview on MSN
Evolution just broke its own logic, a new biology rule may follow
Biologists are closing in on a puzzle that seems to turn classic evolutionary logic inside out, yet may be so common that it ...
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