Across contemporary cardiovascular clinical trials, the estimates of expected event rates and effect sizes that investigators use to calculate sample sizes—and funding requirements—often come in ...

Standard effect sizes are more meaningful outcomes in Alzheimer's disease drug trials than the widely used metric of percent slowing of decline, an analysis suggested. In recent trials of Alzheimer's ...

Basic concepts in hypothesis testing, including effect sizes, type I and type II errors, calculation of statistical power, non-centrality parameter, and applications of these concepts to twin studies.