This figure shows primary T cells modified using two approaches. CAR receptors are introduced through targeted DNA insertion (top), while CRISPRoff mRNA and guide RNAs silence additional genes through ...

There are hundreds of cell types in the human body, each with a specific role spelled out in their DNA. In theory, all it ...

Genetic engineering is moving from the lab bench into clinics, farms, and even family planning decisions, promising to change how we prevent disease, age, and define human potential. The same tools ...

Collaborative research defines a novel approach to understanding how certain proteins called transcription factors determine which genetic programs will drive cell growth and maturation. The method, ...

A new Yale study provides a fuller picture of the genetic changes that shaped the evolution of the human brain, and how the process differed from the evolution of chimpanzees. For the study, published ...

The findings shed new light on human reproduction and suggest pathways for developing treatments to lower the risk of ...

A genetic counselor, though perhaps not as well-known as other healthcare professionals, plays a consequential role on a patient’s healthcare team – namely by helping a patient understand and adapt to ...