N-Glycans on biotherapeutics can affect immunogenicity, pharmacokinetics and pharmacodynamics, making characterization of N-glycans essential in the development process. Here we present rapid N-glycan ...
Glycosylation profoundly affects the efficacy and safety of therapeutic proteins, influencing their biological activity, serum half-life, and immunogenicity. This post-translational modification, ...
The structure of N-linked glycans can play a critical role in the pharmacology of therapeutic proteins, potentially affecting immunogenicity, pharmacokinetics and pharmacodynamics. This makes the ...