The histone code hypothesis posits that distinct combinations of histone modifications can recruit chromatin-modifying enzymes and exert epigenetic control over heterochromatin assembly. In the March ...
Histones are perhaps more intimately linked with DNA than any other protein. Transcriptional regulation, recombination, repair, and replication--basically anything that happens to the DNA--must happen ...
(Philadelphia, PA) - Rearrangements of the mixed lineage leukemia gene, MLL, are associated with aggressive leukemias in both children and adults. Researchers at the University of Pennsylvania School ...
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