The ability to accurately detect heat and pain is critical to human survival, but scientists have struggled to understand on a molecular level exactly how our bodies sense these potential risks. Now, ...

Certain cells, commonly called excitable cells, are unique because of their ability to generate electrical signals. Although several types of excitable cells exist — including neurons, muscle cells, ...

10 October. In tomorrow's Science, researchers describe how developing a new method dubbed "pharmacological knock-in" has enabled them to fill in the missing pieces of an unusual signal transduction ...

Teasing apart the complex circuitry of the brain might someday proceed with the flip of a switch, now that scientists have invented a light-responsive version of a common class of cell-surface ...

Ion channels make good drug targets—they reside on the cell surface and are fast switching mechanisms. They act like cell transistors, controlling many cell processes. There are close to 500 types of ...

The process of expressing a wide variety of voltage-gated and ligand-gated ion channels enables nociceptors to transduce receptor potential into single action potentials or multiple action potentials.

Recent genome projects for ctenophores have revealed the presence of numerous ionotropic glutamate receptors (iGluRs) in Mnemiopsis leidyi and Pleurobrachia bachei, among our earliest metazoan ...

Researchers have identified an ion channel required for brain cells to suppress eating behavior in response to the hormone leptin or to the anti-obesity drug lorcaserin. UT Southwestern Medical Center ...

This is a 3-D computer model of the serotonin 5-HT3 receptor, embedded through a lipid bilayer membrane (horizontal structure with black lines and yellow balls) as it would be naturally in a cell.

BUFFALO, N.Y. – The ability to accurately detect heat and pain is critical to human survival, but scientists have struggled to understand on a molecular level exactly how our bodies sense these ...

Researchers have unraveled the complex biological phenomena that enable the sensing of heat and pain. The ability to accurately detect heat and pain is critical to human survival, but scientists have ...