Background Insomnia symptoms are prevalent in older adults and linked to cardiovascular disease (CVD), but the role of long-term symptom trajectories remains unclear. We investigated associations ...

A newly refined method for measuring the Pace of Aging in population-based studies provides a powerful tool for predicting risks associated with aging, including chronic illness, cognitive impairment, ...

Objective We aimed to investigate the association of cardiorespiratory fitness (CRF) with cognitive function and dementia risk, taking genetic predisposition for dementia into account. Methods Within ...

This population-based study shows that shared and pattern-specific blood biomarkers reflect biological vulnerability underlying multimorbidity and the pace at which chronic diseases accumulate in ...