Clinicians managing lupus nephritis should consider persistent isolated C3 as a possible indicator of long-term renal risk. Persistent isolated low C3 (PILC3) does not appear to predict short-term ...

Largest, most comprehensive cohort of lupus nephritis patients analyzed to date supports soluble ALCAM as a biomarker for disease activity “More targeted therapies are urgently needed to effectively ...

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that ...

Laura holds a Master's in Experimental Neuroscience and a Bachelor's in Biology from Imperial College London. Her areas of expertise include health, medicine, psychology, and neuroscience.View full ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

Biomarkers can serve as early warning signs for individual health and can help indicate certain diseases. In a new study, researchers examined levels of microvascular C5b-9 (a protein found on the ...

Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional ...