MYC proteins play an important role in many types of cancer. A research team at the University of Würzburg has now succeeded in indirectly influencing these proteins—with clear consequences for the ...
MYC family genes are essential for the human organism. According to current knowledge, they regulate the expression of most cellular genes. Misregulation of MYC proteins significantly contributes to ...
The MYC oncogene family plays an important role in neoplastic disease, and has been extensively studied over decades. Evidence showing the N-terminal and C-terminal regions of MYC can function as a ...
The Myc family of transcription factors, including Myc, N-Myc, and L-Myc, bind DNA at specific sequences and regulate gene expression by binding to enhancer-box (E-Box) sequences via dimerization with ...
Chemotherapy drugs are designed to shatter tumor DNA so thoroughly that cancer cells cannot survive. But one of the most common cancer-driving proteins, MYC, appears to run a quiet rescue operation in ...
Researchers at Linköping University show how two important cancer-related proteins can be prevented from collaborating with each other. The discovery shows the way toward future medications to combat, ...
A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according ...
Researchers have shown that c-MYC is an oncogene that drives neuroblastoma in some high-risk patients. Researchers have identified mechanisms that drive about 10 percent of high-risk neuroblastoma ...
18F-fluorothymidine (FLT) PET-CT for early response assessment in advanced pancreatic cancer. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I. This abstract does not include a ...
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