Northwestern Medicine scientists have discovered how calcium signaling channels in microglia—the primary immune cells of the brain—regulate neuroinflammation and promote the development of behaviors ...
Alzheimer's disease (AD) is a highly debilitating neurodegenerative disease characterized by the progressive loss of memory and decline of mental functions. Earlier research has uncovered some of the ...
A sequence of stress signals among specialized clean-up cells in the brain could at last reveal why some immune responses can cause significant nerve degeneration that results in the loss of memory, ...
When microglia wind up with a belly full of lipid droplets, it’s a sign that the cells are rallying, perhaps in vain, to a neurodegenerative threat. But according to a study published July 10 in Cell ...
In trying to treat neuroinflammation, scientists need better ways to visualize microglia in the brains of living people. Current microglial PET tracers target the mitochondrial transporter TSPO, but ...
BOSTON, Feb. 25, 2026 (GLOBE NEWSWIRE) -- Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana”), a biotechnology company developing its lead candidate, intranasal foralumab, a fully human, anti-CD3 ...
A growing body of research points to chronic, low-grade inflammation inside the brain as a possible accelerant of Alzheimer’s disease, not just a bystander response to damage already done. The 2024 ...