Escherichia coli remains at the forefront of recombinant protein production, owing to its rapid growth, well-characterised genetics and the ease with which it can be genetically manipulated. The ...

Bacillus subtilis has emerged as a pre‐eminent model organism for the study and application of protein expression and secretion, owing to its robust secretory pathways and genetic tractability. Its ...

Human genes are written in long strings of three-letter units composed of four different nucleotides. These units—or ...

The cost-effective, easy-to-use T7 expression system has been integral to Escherichia coli protein production since its introduction in 1986. Now, a just-developed enhancement is making it even better ...

This article is based on a poster originally authored by Sunidhi Shetty, Narasimha Murthy Bandaru, Anna Moberg and Marco Manni, which was presented at ELRIG Drug Discovery 2024 in affiliation with ...

The Expi293™ PRO Expression System is a high-performance transient HEK293 mammalian protein expression platform designed to help researchers express more proteins faster, at higher yields, and with ...

A study published in the Proceedings of the National Academy of Sciences has uncovered new clues to why some therapeutic proteins are so difficult to manufacture. The work—led by Nathan Lewis, PhD, ...

Stay up to date on the latest science with Brush Up Summaries. Finally, although transgenic animals and mammalian cell culture systems promote optimal expression due to correct protein modifications, ...

Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...