Each protein or peptide consists of a linear sequence of amino acids. The protein primary structure conventionally begins at the amino-terminal (N) end and continues until the carboxyl-terminal (C) ...

Protein design is crucial for the treatment of human diseases, but traditional protein design methods have some limitations. Site-directed mutagenesis is highly dependent on the physiological ...

Gene sequences are made up of nucleotide bases, which are 'read' by the cell's machinery in triplets; three nucleotide bases are interpreted as one codon, and every codon has a corresponding amino ...

A research team engineered a rigid, nanometer-scale protein module to address the challenge of measuring antibody flexibility ...

During the process of research and development of antibody drug molecules, an essential step is determining the sequence of the antibody. Mass spectrometry technologies have advanced so far as to make ...

A scientist has used a form of artificial intelligence known as deep learning to predict the 3D structure of effectively any protein based on its amino acid sequence. This new approach for ...

By extending a naturally rigid bacterial protein by 50% while preserving geometry and stability, the study introduces protein ...