Researchers have developed the first mouse model for a mitochondrial tRNALeu mutation, showing that the associated metabolic disorder results from faulty RNA processing. Studying the role of ...
New modeling shows how synonymous mutations -- those that change the DNA sequence of a gene but not the sequence of the encoded protein -- can still impact protein production and function. New ...
Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the ...
The functioning of neurons, cells that transmit information in the nervous system, heavily relies on the production of proteins. Proteins are synthesized both inside cells (i.e., in the soma) and ...
Tsukuba, Japan—Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models ...
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