Scheme showing the structure of cytosine, 5-methylcytosine, and 5-hydroxymethylcytosine. Adding a methyl group to the DNA base cytosine represses gene expression in mammalian cells. To remove the ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Researchers developed a reverse translation method that converts protein sequences into DNA, allowing standard DNA sequencers ...

Genomic DNA is organized into chromatin via nucleosomes, regulating its accessibility for critical biological processes such as transcription, replication, and epigenetic modification. The dynamic ...

Artificial intelligence has gotten a bad reputation lately, and often for good reason. But a team of scientists at Google’s DeepMind now claims to have found a revolutionary use case for AI: helping ...

Saliva can provide researchers with a source of high-quality human genomic DNA. Although blood is commonly employed for this purpose, saliva offers several advantages. It is more readily accessible, ...

Next-generation sequencing (NGS), especially long-read DNA sequencing, is transforming infectious organism detection by ...