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NFL Divisional Round odds: Seahawks vs. 49ers spread, line, over/under - January 17, 2026

The Seattle Seahawks host the San Francisco 49ers in the NFC Divisional round of the 2025 NFL Playoffs as touchdown favorites on January 17, 2026 at 8 p.m. ET on FOX.

· 18h · on MSN

49ers vs. Seahawks prediction, odds, time: 2026 NFL divisional round Saturday picks by proven model

SportsLine · 19h

49ers vs. Seahawks line, odds: Proven model releases spread pick for 2026 NFL divisional round matchup on Saturday

· 6h

49ers-Seahawks Divisional Round Game Predicted to End in a Stunner

The San Francisco 49ers advanced to the NFC Divisional Round by outlasting the Philadelphia Eagles 23-19 on Sunday.

· 1d

Seahawks add QB Sam Darnold to injury report for 49ers game

· 1d

Sam Darnold Injury Update, Latest Status for Seahawks vs. 49ers in NFL Playoffs

· 9h

San Francisco 49ers at Seattle Seahawks odds, picks and predictions

San Francisco upset the defending Super Bowl champion Philadelphia Eagles 23-19 in the Wild Card round last week, covering as a 5.5-point road underdog as the Under (44.5) hit.

· 14h

Seahawks vs. 49ers: 3 X-factors on defense for Divisional Round

NFL · 1d

49ers vs. Seahawks: Three must-know storylines for Saturday's Divisional Round game

13d

Seahawks’ offensive line, run game pave way for huge win over 49ers

In the biggest game of the season, it was in large part the Seahawks' offensive line and run game that controlled what took place in a 13-3 win over the 49ers.

4hon MSN

NFL Playoffs: Why Colin Cowherd is confident in Seahawks QB Sam Darnold against 49ers

Fox Sports personality Colin Cowherd shares his predictions for the divisional round matchup between Seattle and Santa Clara.

Richard Sherman Gives Seahawks Blunt Words Before 49ers Game

Richard Sherman delivers blunt remarks to the Seattle Seahawks ahead of their matchup with the San Francisco 49ers.

3don MSN

Seahawks land recently declared defender in latest 2026 NFL mock draft

The Seattle Seahawks land recently declared defender in this latest 2026 NFL mock draft from The Draft Network.

12hon MSN

3 Seahawks players who need to step up vs 49ers after Sam Darnold injury

This Saturday night is the beginning of the Seattle Seahawks’ playoff journey. The No. 1-seeded Seahawks will host the No. 6 San Francisco 49ers in the Division

NO LOVE LOST: Seattle Seahawks, San Francisco 49ers BATTLE for NFC Championship Game Berth

An NFC West grudge match with a trip to the NFC Championship Game is on the line as the Seahawks and 49ers duel once again in the latest installment of their rivalry