Transmission electron microscopy reveals the architecture of cells at nanometer resolution, but chemical fixation severely warps their native structure. The true ultrastructure of cells can be ...

Researchers say the innovation, known as SmartEM, will speed scanning sevenfold and open the field of connectomics to a ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

Electron microscope image of neurons in the cerebellum. This slice through the cells in the cerebellum shows a dendritic branch of a Purkinje cell and its side arms (yellow) receiving several ...

A better understanding of how synapses behave will help the study and treatment of a several medical conditions, especially neurodegenerative diseases such as Huntington’s disease (HD) and ...

Scanning Electron Microscopy (SEM) has revolutionized the realm of microscopic analysis. By delivering astonishingly detailed images of minuscule entities such as insects, bacteria, or even the ...

Connectivity studies are using a variety of imaging approaches to examine circuits at different scales. For example, diffusion magnetic resonance imaging, while unable to resolve individual synapses ...

There are a lot of situations where a research group may turn to an electron microscope to get information about whatever system they might be studying. Assessing the structure of a virus or protein, ...

Since the 1950s, scientists have worked around this problem by coating samples with a thin layer of gold before imaging. While this approach made electron microscopy possible for countless discoveries ...