Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...
Memory formation and maintenance fundamentally rely on intricate molecular processes that regulate synaptic strength. Central to this phenomenon is synaptic plasticity – the capacity of neural ...
Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...
A study mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in affected individuals. The researchers showed the role of three proteins in mediating the ...
By adding, removing, strengthening, or weakening synaptic contacts, our brain encodes new events or forgets previous ones. In AD, synaptic plasticity, the brain's ability to regulate the strength of ...
New research on the hippocampus, a brain area essential for memory, suggests that new rules of synaptic plasticity best explain how brain activity continually reshapes the way memories are recorded in ...
Li’s study, “TIAM1-mediated synaptic plasticity underlies comorbid depression-like and ketamine antidepressant-like actions in chronic pain," was recently published in The Journal of Clinical ...
Astrocytes use the MEGF10 receptor to prune synapses in the striatum, a process essential for dopamine-driven motor learning.
Morning Overview on MSN
Tubulin may be a hidden shield against Alzheimer’s and Parkinson’s
A structural protein best known for building the internal scaffolding of cells may double as a natural defense against the ...
A new study by Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites—not a shared site—to achieve different types of ...
News Medical on MSN
NIH grant supports research on immune-related receptor in neurons
Florida Atlantic University has received a $2.4 million grant from the National Institutes of Health to investigate how an immune-related receptor in neurons plays a fundamental role in brain function ...
As animals experience new things, the connections between neurons, called synapses, strengthen or weaken in response to events and the activity they cause in the brain. Neuroscientists believe that ...
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