The CRISPR systems inside bacteria serve as adaptive immune systems, but they also threaten to unleash autoimmune reactions. Fortunately, for bacteria such as Streptococcus pyogenes, these systems ...

In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting system CRISPR-Cas9 -- as a ...

Interest in genome engineering of mammalian cells has been increasing in the past few years with the development of new tools to create DNA breaks at specific locations on the cell genome. Among these ...

Accurate and Efficient CRISPR Technology Is Paving the Way for Therapeutic Genome Editing Advances in gene-editing technologies have enabled scientists to push forward their understanding of human ...