Unlike an athlete or musician under pressure, most proteins must fold to perform at their best. These large biological molecules fold, bend and twist into unique conformations in order to carry out ...

The death of cells is well regulated. If it occurs too much, it can cause degenerative diseases. Too little, and cells can become tumours. Mitochondria, the power plants of cells, play a role in this ...

Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in the ...

Researchers led by Emanuel Hanski at the Hebrew University of Jerusalem have identified a class of molecules that inhibit endoplasmic reticulum (ER) stress and could decrease mortality in mice ...

The complex 3-D structure of a protein ultimately determines its biological function. As such, maintaining the native conformation is clearly of critical importance if the protein in question is to be ...

PTIR calculates the rates at which originally monomeric proteins are transformed into aggregates at various temperatures under initial-rate settings. Utilizing SMSLS for identical conditions generates ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

A heat shock protein protects the cells against protein clumping. It degrades, however, over longer treatment periods. Plasmas are used, for example, in wound treatment against pathogens that are ...

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and ...