Unlike an athlete or musician under pressure, most proteins must fold to perform at their best. These large biological molecules fold, bend and twist into unique conformations in order to carry out ...

The death of cells is well regulated. If it occurs too much, it can cause degenerative diseases. Too little, and cells can become tumours. Mitochondria, the power plants of cells, play a role in this ...

Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate conformation. Much of this processing occurs in the endoplasmic reticulum ...

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and ...

Scientists continue to be puzzled by how proteins fold into their three-dimensional structures. Small single-domain proteins may hold the key to solving this puzzle. These proteins often fold into ...

PTIR calculates the rates at which originally monomeric proteins are transformed into aggregates at various temperatures under initial-rate settings. Utilizing SMSLS for identical conditions generates ...

The complex 3-D structure of a protein ultimately determines its biological function. As such, maintaining the native conformation is clearly of critical importance if the protein in question is to be ...

Protein design One reason scientists know so little about cold unfolding in comparison to heat unfolding is that it’s difficult to observe in a lab setting. “You need to study the proteins at ...

The death of cells is well regulated. If it occurs too much, it can cause degenerative diseases. Too little, and cells can become tumors. Mitochondria, the power plants of cells, play a role in this ...