Fragment-based drug discovery (FBDD) has gained widespread recognition as a valuable approach in the search for lead drug candidates in drug discovery programs. It is utilized in conjunction with ...

Developing small molecule drugs is expensive, extremely time consuming – and not always successful. Low success-rates have created the need to find and adopt novel ways to quickly and accurately ...

While many of the stages of the cell-mediated immune response are known, the mechanisms by which various white blood cells can specifically bind (and release) to initiation proteins are not as well ...

How proteins interact with each other has become a key issue in drug discovery and development. Once a target for a drug is identified, it is also important to define how strongly it binds to other ...