Although CRISPR-Cas has found many uses in biotechnology and medicine, it originates in nature, where it functions as a microbial immune system. Scientists shed new light on how CRISPR-Cas emerged ...

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The microbes of the world are constantly competing with one another. There are viruses that can infect bacteria, called bacteriophages, and bacteria have ways to defend against the phages, which some ...

A compact and efficient CRISPR-Cas system, named CasMINI, could be broadly useful for cell-engineering and gene-therapy applications because it is easier to deliver into cells. The findings appear in ...

Although existing CRISPR-Cas-based imaging methods can target endogenous genomic sequences, their applications are limited by ...

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Cas3, which shreds where Cas9 snips, has been used to chew up long stretches of DNA. Even better, it has done so with precision, a quality seldom associated powerful shredding tools. Combining ...

Why grab just a pair of scissors when you could get more functionality with a Swiss knife? A team of researchers at Stanford University think they've built such a tool to apply to CRISPR gene editing, ...

Bioengineers have repurposed a 'non-working' CRISPR system to make a smaller version of the genome engineering tool. Its diminutive size should make it easier to deliver into human cells, tissues and ...