Codon-optimization describes gene engineering approaches that use synonymous codon changes to increase protein production. It is used extensively for expressing recombinant protein drugs, gene therapy ...
A study conducted by researchers at Ohio State University and the New York University Grossman School of Medicine in the USA, has revealed that optimization of codon for bacterial expression causes ...
Figure 2: FRQ activities in circadian feedback loops are impaired in the frq codon-optimized strains. Figure 3: FRQ protein in the codon-optimized strains is less stable and more sensitive to trypsin ...
Earlier this year, we projected that 2021 would be the year of quantum computing for drug discovery, positing the idea that this is one of only a few areas where there is big ROI to offset the work ...
Healthy life expectancy of colorectal cancer survivors. Background: KRAS genotyping represents a first step towards individualized therapy and has become a crucial issue in mCRC. The optimization of ...