Proteins serve as the molecular workhorses governing virtually every biological process, making their quantitative analysis crucial for understanding cellular dynamics, disease mechanisms, and ...

Single-cell RNA sequencing (scRNA-seq) has transformed the field of transcriptomics by making it possible for researchers to address fundamental questions that could not be tackled by bulk-level ...

We have assessed the utility of RNA titration samples for evaluating microarray platform performance and the impact of different normalization methods on the results obtained. As part of the ...

Comparison of expression data requires normalization. The optimum normalization method depends on sample type, with the most common being to normalize to reference genes. It is critical to select ...

See a spike in your DNA–protein interaction quantification results with these guidelines for spike-in normalization. A team of researchers at the University of California San Diego (CA, USA) have ...

Dr. James McCaffrey of Microsoft Research uses a full code sample and screenshots to show how to programmatically normalize numeric data for use in a machine learning system such as a deep neural ...