Dec 5, 2014 · Apolipoprotein E (ApoE) is a critical signal for synaptogen-esis and synaptic maturation [101]. ApoE/cholesterol com-plex released from astrocytes is taken up through low …
is lower in apoE4 transgenic mice compared with apoE3 mice, indicating impaired synaptogen-esis (12, 13). ApoE4 is less efficient than apoE3 in transporting brain cholesterol (14) and is …
Traumatic brain injury (TBI) is a frequent consequence of vehicle, sport and war related injuries. More than 90% of TBI patients suffer mild injury (mTBI). However, the pathologies underlying …
Neurotrope Launches New Long-Term Clinical Trial of
NEW YORK, May 28, 2020 – Neurotrope, Inc. (Nasdaq: NTRP) today announced the launch of a new long-term study of Bryostatin-1 for the treatment of patients with Alzheimer’s disease …
Neurotrope Announces Publication Highlighting the Potential of ...
The complete publication in the Trends in Pharmacological Sciences: CellPress Reviews can be accessed here: https://www.synaptogen.com/wp-content/uploads/2019//08/TiPS2019.pdf and …
Abhik Sen, Jarin Hongpaisan, Desheng Wang, Thomas J. Nelson and Daniel L. Alkon.
Synaptogenix | Neurotrope, In Consultation With Leading …
The Company has selected Worldwide Clinical Trials (Worldwide) to conduct this confirmatory Phase 2 clinical trial. Worldwide is a leading global clinical research organization and the …
PKC Activation Prevents Synaptic Loss, A Elevation, and Cognitive Deficits in Alzheimer’s Disease Transgenic Mice Jarin Hongpaisan,1,2 Miao-Kun Sun,1 and Daniel L. Alkon1
Morgantown, WV 26505 Running title: Rescuing synapses and spatial memory in young fragile X mice
Neurotrope Announces Publication Demonstrating Synaptic …
Bryostatin, currently being tested in a Phase 2b clinical trial in Alzheimer’s Dementia, causes regeneration of synaptic networks in both Alzheimer’s and Fragile X mouse models, …