The coat protein complex II, or COPII, is a group of proteins that facilitate the formation of vesicles to transport proteins from the endoplasmic reticulum to the Golgi apparatus or endoplasmic …

Mar 25, 2025 · Coat protein complex II (COPII) subunits assemble to form membrane transport carriers at ER exit sites, thereby concentrating secretory cargoes and facilitating their transport to the Golgi.

Jan 1, 2011 · Coat protein complex II (COPII) is a set of highly conserved proteins that is responsible for creating small membrane vesicles that originate from the endoplasmic reticulum (ER) (Lee et al., …

COPII refers to a coat complex that is crucial for the sorting and transport of newly synthesized biosynthetic cargo from the endoplasmic reticulum to the Golgi apparatus, consisting of the small …

Here we describe progress towards a full mechanistic understanding of COPII coat function, including the latest findings in this area. Much of our understanding of how COPII functions and is regulated …

Sep 17, 2013 · Coat protein complex II (COPII) mediates formation of the membrane vesicles that export newly synthesised proteins from the endoplasmic reticulum. The inner COPII proteins bind to cargo …

Jan 12, 2021 · The coat protein complex II (COPII) mediates forward trafficking of protein and lipid cargoes from the endoplasmic reticulum. COPII is an ancient and essential pathway in all eukaryotes …

Jul 24, 2025 · COPII vesicles are microscopic packages within cells, acting as fundamental transport carriers. These tiny, membrane-bound sacs are responsible for moving newly made proteins and …

Dec 22, 2011 · The cytoplasmic coat protein complex II (COPII) is responsible for cargo sorting and vesicle morphogenesis.

Jun 18, 2018 · Structural and functional studies have shown that the COPII coat is both highly flexible and subject to multiple modes of regulation. This has led to new discoveries defining roles of COPII …