This article addresses frequently asked questions (FAQs) related to the Centiloid scale, summarizes the available literature on Centiloid thresholds using different reference …

Amyloid‐PET quantification through the tracer‐independent Centiloid (CL) scale has emerged as an essential tool for the accurate measurement of amyloid‐β (Aβ) pathology in Alzheimer's …

Jan 1, 2025 · This article addresses frequently asked questions (FAQs) related to the Centiloid scale, summarizes the available literature on Centiloid thresholds using different reference …

Background: The Centiloid method (CL) was introduced as a tracer-independent measure for cortical amyloid load and is now commonly used in Alzheimer’s disease (AD) clinical trials.

Sep 21, 2025 · Learn how the Centiloid Scale standardizes amyloid PET imaging, bringing clarity to Alzheimer’s research, diagnosis, and treatment.

Discover how MIMneuro® standardizes amyloid PET quantification with the Centiloid scale. Learn about calibration methods and overcoming variability in PET tracers.

Calibration to the Centiloid scale allows units that are more easily compared across sites. All data used in the Centiloid Project is available for download in the pages below.

Jan 9, 2025 · Compared to histopathology (gold standard), visual reads, and cerebrospinal fluid (clinical standards), Centiloid quantification accurately reflects the amount of AD pathology.

The Centiloid scale has been developed to standardize measurements of amyloid PET imaging. Reference cut-off values of this continuous measurement enable the consistent …

The Centiloid scale is from 0 to 100, with 0 CL reflecting a negative result (amyloid burden of a young healthy normal group) and 100 CL reflecting patients who are positive (extensive …