Feb 15, 2021 · Coombs test / DAT is used to determine whether a patient’s red blood cells (RBCs) are coated with immunoglobulins or complement in vivo

Nov 28, 2023 · The pediatric hematologist is concerned about autoimmune hemolytic anemia and orders a direct antiglobulin test (DAT), which is negative and requests a peripheral blood smear, which …

Jul 19, 2021 · Positive Coombs test, evidence of extravascular rather than intravascular hemolytic anemia (Oxf Med Case Reports 2020;2020:omz125) Various presentations of microangiopathic and …

Oct 19, 2023 · Practice question #1 Which of the following is considered the definitive test for diagnosis of paroxysmal cold hemoglobinuria (PCH)? Bone marrow biopsy Coombs test Donath-Landsteiner …

Feb 26, 2025 · Performing a direct Coombs test may help detect the presence of autoantibodies For cases involving cold autoantibodies or cold reactive alloantibodies, incubating the red cells at 37 °C …

Jun 25, 2021 · DAT: direct antiglobulin test AHTR: acute hemolytic transfusion reaction CBC: complete blood count LDH: lactate dehydrogenase PT: prothrombin time APTT: activated partial …

Jul 20, 2020 · The patient's direct antiglobulin test is 3+ positive for IgG and negative for C3d. The elution demonstrates the presence of anti-C and anti-Fya. The patient's phenotype, using a sample …

Mar 15, 2024 · Hemolytic uremic syndrome / thrombotic thrombocytopenic purpura (HUS/TTP) is an endothelial injury with microvascular thrombi, often due to infection, complement disorders or …

Oct 15, 2024 · Warm autoantibody is an antibody that binds to the patient's own red blood cells (RBCs) and reacts optimally at 37 °C (body temperature) Identified in routine blood bank testing (e.g., type …

Feb 10, 2025 · Negative direct antiglobulin test (DAT) (i.e., Coombs test) Elevated cardiac troponins or lactate Schistocytes on peripheral blood film or complete blood count (CBC) differential (see …