COPII - Wikipedia
The coat protein complex II, or COPII, is a group of proteins that facilitate the formation of vesicles to transport proteins from the endoplasmic reticulum to the Golgi apparatus or endoplasmic …
Mechanisms of COPII coat assembly and cargo recognition in the ...
Mar 25, 2025 · This Review discusses the mechanisms of coat assembly and disassembly, and cargo recognition by COPII carriers.
COPII - an overview | ScienceDirect Topics
COPII refers to a coat complex that is crucial for the sorting and transport of newly synthesized biosynthetic cargo from the endoplasmic reticulum to the Golgi apparatus, consisting of the small …
COPII-mediated vesicle formation at a glance - The Company of …
Jan 1, 2011 · Coat protein complex II (COPII) is a set of highly conserved proteins that is responsible for creating small membrane vesicles that originate from the endoplasmic reticulum (ER) (Lee et al., …
Assembly, organization, and function of the COPII coat - PMC
Here we describe progress towards a full mechanistic understanding of COPII coat function, including the latest findings in this area. Much of our understanding of how COPII functions and is regulated …
Export Control: Post-transcriptional Regulation of the COPII ...
Jan 12, 2021 · COPII is an ancient and essential pathway in all eukaryotes and COPII dysfunction underlies a range of human diseases. Despite this broad significance, major aspects of COPII …
COPII Vesicles: What They Are and How They Work
Jul 24, 2025 · COPII vesicles are microscopic packages within cells, acting as fundamental transport carriers. These tiny, membrane-bound sacs are responsible for moving newly made proteins and …
The structure of the COPII transport-vesicle coat assembled on ...
Sep 17, 2013 · Coat protein complex II (COPII) mediates formation of the membrane vesicles that export newly synthesised proteins from the endoplasmic reticulum. The inner COPII proteins bind to cargo …
COPII collar defines the boundary between ER and ER exit site and …
Live-cell and electron microscopy revealed a novel mode of function for COPII during cargo export from the ER. COPII is recruited to membranes defining the boundary between the ER and ER exit sites, …
COPII and the regulation of protein sorting in mammals - Nature
Dec 22, 2011 · COPII was first described in Saccharomyces cerevisiae, but its basic function is conserved throughout all eukaryotes. Nevertheless, the COPII coat has adapted to the higher …