The meaning of SUBSTANCE is essential nature : essence. How to use substance in a sentence.

Any material that possesses physical properties is called a substance. The word also refers to the gist or main idea of something. If you remember the main point of a lesson, you've got the …

Substance definition: that of which a thing consists; physical matter or material.. See examples of SUBSTANCE used in a sentence.

SUBSTANCE definition: 1. material with particular physical characteristics: 2. an illegal drug: 3. the most important…. Learn more.

the actual matter of a thing as opposed to its appearance:[uncountable] form and substance. Chemistry a particular kind of material, as of a definite chemical composition:[countable] a …

A drug, chemical, or other material (such as glue) that one is dependent on or uses habitually and that is often illegal or subject to government regulation: Which substance was he abusing?

Definition of substance noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.

Discover everything about the word "SUBSTANCE" in English: meanings, translations, synonyms, pronunciations, examples, and grammar insights - all in one comprehensive guide.

Sep 14, 2025 · Borrowed from Latin substantia (“substance, essence”), from substāns, present active participle of substō (“exist”, literally “stand under”), from sub + stō (“stand”).

There are 35 meanings listed in OED's entry for the noun substance, ten of which are labelled obsolete. See ‘Meaning & use’ for definitions, usage, and quotation evidence.